Dynamically collaborate, compare, track, and finalize peptide results and workbooks using versioning history.
Moler mass finder software#
BioPharma Finder software with HyperBridge software enables an all-encompassing solution for peptide mapping analysis including data processing, review, and reporting. By leveraging the HRAM data produced by Orbitrap mass spectrometers that reveal the unique abundance distribution of the sulfur isotopes, BioPharma Finder software automatically computes the chemical formula for phosphorothioated molecules and uses this information to generate a sequence-specific isotopic model, in order to obtain accurate deconvolution results.īioPharma Finder software simplifies comprehensive biotherapeutic attribute characterization with advanced capabilities to increase throughput and confidence for BioPharma workflows with built for purpose data processing, curation, and reporting in a connected environment to streamline and enable collaboration on a global scale powered by Thermo Scientific HyperBridge software.Ĭonnectivity streamlines and enables collaboration on a local and global scale with seamless data processing capabilities by multiple users across any computer connected to the virtual private cloud or on-premises server. One of the most frequently used modifications are phosphorothioates, which replace oxygen with sulfur in the linker region. Incorporation of chemical modifications into therapeutic oligonucleotides in order to resist degradation by naturally occurring nucleases is common. With improved detection of low abundance species using the Sliding Window algorithm, powerful data visualization tools allow you to gain structural insights into your protein with confidence. Whether you are analyzing your protein under denaturing conditions or in its native state or determining the mass of a heavily modified oligonucleotide therapeutic, default methods and an automated parameter optimizer deliver accurate and confident deconvolution, simplifying your analyses.īioPharma Finder software can perform batch-to-batch comparisons, or help you confirm the identity of antibody-drug conjugates (ADCs). Comprehensive oligonucleotide analysis capabilities enable the identification and detection of impurities, metabolites, and the sequence mapping of large mRNA therapeutics.
Fully characterize protein-based therapeutics using peptide mapping analysis to provide complete sequence confirmation, post-translational modifications (PTMs), disulfide bonds, host cell proteins, and hydrogen-deuterium exchange (HDX). Workflows guide experts and non-experts to easily set up, interpret and visualize results, accessing the information contained within any analyzed sample. Simplify and streamline your analysis workflows using a single software platform including everything from batch processing to in-depth data analyses. From novel deconvolution algorithms generating complete results to easy-to-understand data visualization tools, Thermo Scientific BioPharma Finder software helps you choose the right path for confident characterization. Access workflows that facilitate comprehensive interpretation and data visualization, allowing you to confidently characterize your biologics with speed and ease. Complete biotherapeutic characterization includes intact mass analysis, peptide mapping, oligonucleotide analysis, top- and middle-down analysis or Multi-Attribute Method (MAM) workflows.
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